Molecular Biology Grade Nanodiamonds
Yorkshire Bioscience offers modified Nanodiamonds (Molecular Biology Grade) with unique properties for physical, chemical and biology applications. Our first two products - NanoD1 and NanoD2 - are high purity homogeneous state nanodiamonds treated according to our proprietary technology. Our short-term plan is to introduce modified nanodiamonds with surface functional groups for conjugation to nucleic acid and protein molecules. Detonation nanodiamonds are of great interest for biochemistry and molecular biology because of their unique physicochemical properties, such as a highly developed surface of particles (270–280 m2/g) with a large number of surface ionogenic (carboxyl, carbonyl, hydroxyl, ether) groups, hydrocarbon fragments, and metal microimpurities. Taken together, these factors allow one to treat nanodiamonds as new sorbents suitable for the separation, purification and immobilization of nucleic acids and proteins. DNA molecules attached to diamond surfaces are accessible to enzymes, and can be modified in surface enzymatic reactions. Direct comparisons of DNA-modified diamond surfaces with other commonly used surfaces, such as gold, silicon, and glassy carbon, showed that the modified diamond surfaces possessed excellent specificity and chemical stability under the conditions of repeated DNA hybridization/denaturation cycles (Lu, M. et al., Biopolymers, 2004).
Physics of the Solid State 2004, 46 ( 4), 758–760. Translated from Fizika Tverdogo Tela,2004 46(4), 737–739. Doklady Biochemistry, 2000, 373, 142–144. Translated from Doklady Akademii Nauk 2000, 373 (4) 547–549.
Electroanalysis 2003, 15(3): 169-174. J.Solid State Electrochem. 2001, 5: 88-93. J.Solid State Electrochem. 2001, 5: 313-318
Biopolymers, Vol. 73, 606–613 (2004)
J. Surf Interface Anal 2001, 32, 3–9. J. Nat Mater 2002, 1, 253–257. Langmuir 2003, 19, 1938–1942.
*Compared to the raw material.
NanoD1
NanoD2
Both products are available in bulk quantities >100g. Please inquire price here. |
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