Oligonucleotides Synthesis Service
15-150 nt-long, any scale and modifications
Oligonucleotides synthesis:
Quality:
Reverse phase purification of oligonucleotides as standard procedure
Delivery:
3, 5 and 7 working days for unmodified, single-, and double- labelled
oligonucleotides respectively.
Ordering via:
email ( sales@york-bio.com),
fax (01904 567 621), mail, or
online order form
Price starts
from
30p/base (10 nmole scale).
Discounts: 10% off the price for
>10 oligos/order.
Report:
Complete documentation is enclosed.
Your Choice:
Let us know if you would like to receive oligonucleotides dissolved in water or
TE at working concentration.
Standard Oligonucleotides:
Synthesis Scale |
Number of Bases |
Yield (20-mer) |
Purification |
Price/base, (£) |
10 nmole |
15 - 35 |
2 OD |
RPC* |
0.40 |
40 nmole |
15 - 80 |
4 OD |
RPC* |
0.50 |
40 nmole |
80-150 |
2 OD |
HPLC** |
1.20 |
0.2 µmole |
15 - 80 |
15 OD |
RPC* |
0.80 |
1.0 µmole |
15 - 80 |
50 OD |
Gel-filtration |
1.80 |
10 µmole |
15-50 |
400 OD |
HPLC, £250 |
15.0 |
15 µmole |
15-50 |
600 OD |
HPLC, £350 |
18. 0 |
Purification: *RPC (reverse phase chromatography)
and gel-filtration are free of charge. HPLC** purification for 1 µmole and below -
£20.
Prices on Labelled
Oligonucleotides (15-80 bases), including HPLC purification:
Label or Modification |
10 nmole |
40 nmole |
0.2 µmole |
1.0 µmole |
Unit |
Standard DNA |
£0.40 |
£0.50 |
£0.80 |
£1.80 |
base |
Phosphorothioate |
£5.80 |
£7.50 |
£8.50 |
£12.00 |
base |
5’-Amino |
£50 |
£6 0 |
£ 75 |
£85 |
oligo |
3’-Amino |
£50 |
£ 60 |
£ 75 |
£ 85 |
oligo |
5’-Phosphorylation |
£ 50 |
£ 60 |
£ 75 |
£ 85 |
oligo |
3’-Phosphorylation |
£ 40 |
£ 50 |
£ 80 |
£100 |
oligo |
Biotin |
£50 |
£6 0 |
£ 75 |
£ 85 |
oligo |
FITC |
£ 40 |
£ 60 |
£ 75 |
£85 |
oligo |
TRITC |
£4 0 |
£ 60 |
£ 75 |
£85 |
oligo |
6-Fam |
£6 0 |
£ 80 |
£ 95 |
£12 0 |
oligo |
Tet |
£6 0 |
£ 80 |
£ 95 |
£12 0 |
oligo |
Hex |
£6 0 |
£ 80 |
£ 95 |
£12 0 |
oligo |
6-Rox |
£80 |
£90 |
£110 |
£160 |
oligo |
6-Joe |
£80 |
£90 |
£110 |
£160 |
oligo |
6-Tamra |
£80 |
£90 |
£110 |
£160 |
oligo |
Texas Red |
£80 |
£90 |
£110 |
£160 |
oligo |
Cy5 |
£80 |
£90 |
n/a |
n/a |
oligo |
Cy3 |
£80 |
£90 |
n/a |
n/a |
oligo |
DNP (Dinitrophenyl) |
£6 0 |
£ 80 |
£ 95 |
£12 0 |
oligo |
Dabsyl |
£6 0 |
£ 80 |
£ 95 |
£12 0 |
oligo |
Dual labelled oligonucleotides,
including 2×HPLC: Possible
dyes at 5’: 6-Fam, Hex, Tet
Possible dyes at 3’: Tamra, Rox,
Joe |
£240 |
£300 |
£400 |
£800 |
oligo |
Guaranteed yield |
1.0 OD |
2.0 OD |
5.0 OD |
15.0 OD |
oligo |
For oligos shorter than 15 or longer than 80 bases,
please
enquire.
|