A Single Nucleotide Polymorphism (SNP)
arises when a nucleotide
within a genome can exist
as one of two variants. SNPs arise
every 500–1000 bases in
the human genome. The special virtues of SNPs
for genetic
analysis are their ease of discovery and assay. Their high
density in the human
genome and their effects, in some cases, on
transcription and
translation make SNPs valuable for
association
studies.
The genomic DNAs that we supply
were isolated from a number of healthy and diseased people. All clinical
data are available. Clinical descriptions meet corresponding
international requirements and were approved by specialists. In some
cases, histological slides are available.
The number of DNA samples
in collections is variable. We are able to collect and describe
more than 100 samples from diseased and healthy patients upon request.